Glenn Foundation Awards $2 Million to MIT for Aging Research

The Massachusetts Institute of Technology has announced a $2 million grant from the Glenn Foundation for Medical Research to establish a center for the study of aging.

The Paul F. Glenn Center for Science of Aging Research at MIT will incorporate research initiatives in the Department of Biology, the Picower Institute for Learning and Memory, and the David H. Koch Institute for Integrative Cancer Research at MIT, building on research conducted by the Paul F. Glenn Laboratory for Science of Aging Research, which was established in 2008 with a $5 million gift from the foundation. Areas of focus will include the role of sirtuin activation and nicotinamide adenine dinucleotide supplementation in slowing the aging process and diseases of aging, stem cell analysis of the structures that support the maintenance of genome integrity as it relates to cognitive decline and neurological disorders in the aging brain, and single-cell sequencing to assess the chromosomal landscape during aging and in age-associated diseases, further elucidating the role of aneuploidy, a chromosomal disorder, in aging.

"With this generous gift, the Glenn Foundation will enable us to carry out a multitiered approach and leverage the strengths of all three labs to arrive at new and testable conclusions about what pathways and mechanisms govern aging," said Novartis Professor of Biology Leonard Guarente, who will direct the center. "Behind all of our research is the drive to discover new therapeutic compounds that have the potential to improve the course of the aging process and hopefully lead the way toward effective treatments for neurodegenerative diseases like Alzheimer's disease and Parkinson's disease, as well as cancer."

"Glenn Foundation Gift to MIT to Fund Multiple Research Initiatives on How We Age." Massachusetts Institute of Technology Press Release 06/25/2015.