The Michael J. Fox Foundation for Parkinson's Research in New York City has announced thirty-nine grants totaling more than $5 million in support of Parkinson's disease research.
The grants will support projects focused on defining the causes of and factors that account for variability in Parkinson's; new methods of diagnosing the disease; and effective treatments to stop or slow its progression. The funding also will support projects focused on developing critical research tools the field needs to advance, including assays, cell lines, and DNA plasmids.
Recipients include Robert H. Edwards (University of California, San Francisco), who will use his grant to examine how rare genetic mutations change the function of alpha-synuclein, a protein present in those suffering from Parkinson's that scientists believe is toxic to cells; Yuanfang Guan (University of Michigan), who is developing learning models for use in interpreting data collected from wearable devices; and Jennifer A. Johnston (An2H Discovery), who is testing activators of the parkin pathway. Parkin, a protein, plays a role in dopamine cell health, and some people with Parkinson's have lowered parkin function.
For a complete list of funded projects, see the MJFF website.