The mission of the Melanoma Research Alliance is to end suffering and death due to melanoma by collaborating with all stakeholders to accelerate powerful research, advance cures for all patients, and prevent more melanomas.
To that end, MRA has issued a Request for Proposals for its Established Investigator Award.
Grants of up to $125,000 a year for up to three years ($375,000 total) will be awarded to senior investigators with an established record of scientific productivity and accomplishment in support of preclinical, translational, and early clinical research with the potential to produce near-term advancements in melanoma prevention, detection, diagnosis, staging, and treatment. MRA is interested in proposals that address the gap in translational science (i.e., turning scientific discoveries into tools and/or treatments for high-risk individuals and patients with melanoma).
Special emphasis areas for the 2020-21 grant cycle are focused on current unmet clinical needs in melanoma. Of particular interest are proposals that identify strategies for overcoming primary and secondary treatment resistance; development of treatment strategies for difficult-to-treat melanoma subtypes such as acral, mucosal, or uveal melanoma, and/or non-BRAF mutant melanomas, including NRAS and NF1 mutants; uncovering novel mechanisms of melanoma initiation and progression in order to improve prevention and early-detection strategies, develop early treatment approaches such as adjuvant and neoadjuvant therapies, and identify prognostic biomarkers of high-risk disease/precursor lesions; and strategies to prevent and/or treat metastatic disease, including in transit and/or satellite metastases and leptomeningeal disease.
To be eligible, principal investigators (PIs) must hold a full-time faculty appointment at the level of assistant professor or above at an academic or other nonprofit research institution in or outside the United States an be past the initial four years of their first academic faculty appointment.
See the Melanoma Research Alliance website for complete program guidelines and application instructions.