To improve understanding and quantify exposures to various concentrations of both endogenous and exogenous hormones for breast cancer risk in California, the California Breast Cancer Research Program (CBCRP) is looking to fund two pilot studies to provide the evidence needed to characterize the drugs and hormones in the state's food and water supply:
Project I (Hormones in Beef) — Characterize the presence of seven FDA-approved drugs in beef products sold in California. Under the study, beef products would be examined for endogenous hormones (testosterone propionate [TP], estradiol [E2] and estradiol benzoate, and progesterone) and synthetic hormones (trenbolone acetate [TBA], zeranol, and melengestrol acetate [MGA]). Samples would be collected from retail stores in the state of California. Beef sampling should evaluate both conventionally produced and USDA-Certified Organic samples for endogenous hormones.
Project II (Hormones in Well Water) — Characterize the presence of seven FDA-approved drugs for use in beef production in California's well water. The study should examine the same seven drugs as in Project I: endogenous hormones (testosterone propionate [TP], estradiol [E2] and estradiol benzoate, and progesterone) and synthetic hormones (trenbolone acetate [TBA], zeranol, and melengestrol acetate [MGA]). Research should be conducted in a cross-section of California households at potential risk of contamination due to effluent from large-scale animal production and dairy facilities. Depending on the results, the data could be paired with geo-referenced data on animal production sites, which would allow for analyses of spatial relationships between animal production and groundwater contamination with hormones.
Funding of up to $200,000 (maximum direct costs) over two years will be awarded to any individual or organization in California. The research must be conducted primarily in California.
CBCRP will host an informational webinar on Wednesday, September 25, from 1:00–2:00 pm PDT, in which it will cover the purpose of the RFP, how applications will be reviewed, and how to apply for the funding opportunity. (Register here.)
For additional information, see the California Breast Cancer Research Program website.