Lupus Research Alliance Seeks LOIs for Global Team Science Awards

The Lupus Research Alliance is inviting Letters of Intent for its Global Team Science Awards.

Through the program, grants of up to $3 million over three years will be awarded to established investigators across scientific disciplines and geographies who are positioned to make major advances in understanding the heterogeneity of systemic lupus erythematous (SLE) using highly collaborative, synergistic, and innovative approaches.

Investigators are encouraged to apply through the LOI process for four-month planning grants of up to $10,000 each to assemble a team that can develop and submit a full application. LRA anticipates that up to six planning grants and up to three Global Team Science Awards will be awarded.

Examples of the type of questions that could be explored under the Global Team Science Award include but are not limited to the following: understanding functional consequences of variants, genes, and pathways implicated by human genetic studies; understanding the role of the microbiome in lupus development and/or progression; characterizing the immunologic, genetic, and molecular factors differentiating responders and non-responders to approved and/or investigational therapies in SLE; correlating clinical subsets of SLE with peripheral biomarkers; understanding how the mechanisms of disease differ for different clinical manifestations of lupus; defining genetic and/or molecular factors conferring susceptibility to developing lupus nephritis; and utilizing the Accelerating Medicines Partnership (AMP) SLE samples/data or other high-quality samples/data sets to examine racial and ethnic differences in key cellular/molecular pathways.

To be eligible, applicants must have an MD, PhD, DVM or equivalent academic degree and hold a faculty position or equivalent at a college, university, medical school, or comparable institution. Applications may be submitted by public or private domestic or foreign nonprofit organizations such as colleges, universities, hospitals, or laboratories. There are no geographic restrictions or citizenship requirements for applicants, and researchers working outside the U.S. are encouraged to apply.

See the Lupus Research Alliance website for complete program guidelines and application instructions.

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Deadline: April 10, 2020