Cystic Fibrosis Foundation Invites Applications for Pilot and Feasibility Awards

The mission of the Cystic Fibrosis Foundation is to cure cystic fibrosis and provide all people with CF the opportunity to lead a long, fulfilling life.

To advance this mission, the foundation welcomes applications for its Pilot and Feasibility Awards program. Through the program, grants of up to $50,000 per year (plus 12 percent for indirect costs) for up to two years will be awarded in support of basic research studies focused on the development and testing of new hypotheses in areas relevant to cystic fibrosis. Information derived from such studies must have the potential to lead to submission to other funding agencies such as the National Institutes of Health. Proposed work must be hypothesis-driven and must reflect innovative approaches to critical questions in CF research.

Priority will be given to projects that propose to better understand the mechanisms behind disease pathophysiology and develop strategies to prevent or treat CF. Emerging areas of interest with high priority to the CF Foundation include direct and indirect influences of CFTR modulation on the airway milieu, including resident pathogens, inflammation and inflammatory cell function, mucin structure (tethered and secreted), airway surface liquid (ASL), and mucociliary clearance; mechanisms of defective MCC and ASL that are relevant for therapeutic applications; biological mechanisms involved in lung allograft dysfunction/rejection and transplant immunology; improved understanding of acquisition, detection, pathogenesis, host-pathogen interactions, and treatment approaches for difficult-to-treat CF infections (i.e., NTM, MDR pseudomonas, MRSA, aspergillus, burkholderia, stenotrophomonas); approaches to understanding and treating CF-related GI complications, including liver disease and the impact of nutritional deficiencies; and the effects of endocrine system dysfunction in CF, including Cystic Fibrosis Related Diabetes (CFRD) and CF bone disease.

To be eligible, applicants must be an independent investigator. U.S. residents and applicants from outside the U.S. are welcome to apply.

See the Cystic Fibrosis Foundation website for complete program guidelines and application instructions.

View another RFP related to medical research

Deadline: April 30, 2021